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Cough Hypersensitivity _ Cough hypersensitivity as a neuro-immune interaction

Di: Henry

Main body Both central and peripheral neural pathways regulate cough, and although mechanisms driving development of cough hypersensitivity are not fully known, sensitization of Cough reflex hypersensitivity is emerging as a key treatable trait in chronic cough and other cough-associated respiratory conditions. This review examines the neurological

Cough and cough hypersensitivity as treatable traits of asthma

Abstract In children and adults, chronic cough is a common symptom presenting to health professionals worldwide. It is internationally accepted that children with chronic cough should Haduvio acts as a kappa agonist and a mu antagonist (KAMA), which are opioid receptors that play a key role in controlling cough hypersensitivity, which is thought to be the link across On this basis, chronic cough may in many cases be best considered a disease entity in its own right. Hitherto putative ‘causes’ of chronic cough, such as asthma and GORD,

Management of chronic refractory cough | The BMJ

Cough hypersensitivity syndrome is the umbrella term used to describe the excessive stimulation of the normal cough reflex caused by thermal, chemical, or mechanical stimulation. Mithilfe der deutschen Version des Hull Cough Hypersensitivity-Fragebogens have been investigated kann eine kurze, strukturierte Anamnese, mit Hinweis auf eine Reflux-Husten-Korrelation benützt werden. Cough reflex hypersensitivity is emerging as a key treatable trait in chronic cough and other cough-associated respiratory conditions.

Abstract Chronic cough has been suggested to be due to three conditions, asthma, post nasal drip, and reflux disease. A different paradigm has evolved in which cough is viewed as the

Mit einem Fragebogen z. B. (Hull-Cough-Hypersensitivity-Fragebogen) können Trigger besser erkannt, aktiv vermieden und Therapieerfolge im Verlauf dokumentiert werden. For cough hypersensitivity in adults, speech and language therapy and neuromodulators (eg, gabapentin) could be considered. In children, there is no consistent association of asthma with Introduction Cough is common in interstitial lung disease (ILD) and is associated with disease progression, yet its mechanisms are understudied. We investigated cough

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  • Cough and cough hypersensitivity as treatable traits of asthma
  • Cough Reflex Hypersensitivity as a Key Treatable Trait
  • Are you Aware of Cough Hypersensitivity Syndrome?
  • DEGA Leitlinie AFRegisterr. 13 Husten Kurzversion

Cough hypersensitivity may improve with treatment of other treatable traits, if not the patients hypersensitivity in adults has refractory CC (RCC). In RCC, the most effective treatments are those addressing cough

Does cough hypersensitivity syndrome differ from a chronic cough? Experts define it as a cough in response to a stimulus. Whereas persistent or chronic cough lasts for at least eight weeks. The Chronic cough is considered a disorder of neuronal hypersensitivity in which patients frequently report abnormal laryngeal and chest sensations, and excessive triggers. To facilitate clinical

In children and adults, chronic cough is a common symptom presenting to health professionals of cough worldwide. It is internationally accepted that children with chronic cough should

Refractory chronic cough has been dis-cussed in the literature and clinical practice under several different names, including neurogenic cough, laryngeal hypersensitiv-ity, cough hypersensitivity The cough hypersensitivity syndrome was clearly endorsed by the opinion leaders as a valid and useful concept. They considered that support of patients with chronic cough was inadequate This PrimeView highlights the mechanisms underlying chronic cough and cough hypersensitivity syndrome, and accompanies the Primer article on this topic by Mazzone et al.

Cough hypersensitivity as a neuro-immune interaction

The newly described paradigm and entity of cough hypersensitivity syndrome (CHS) becomes useful when the etiology of cough remains elusive or when the cough remains Cough Hypersensitivity Syndrome (CHS) serves as a paradigm for understanding chronic refractory cough. CHS is chronic cough triggered 18 Therapie nach RKI-Empfehlung nein 19 Upper Airway Cough Syndrom ? ja 20 Intranasale Kortikosteroide

Chronic cough is globally prevalent across all age groups. This disorder is challenging to treat because many pulmonary and extrapulmonary conditions can present with chronic cough, and Current antitussives have limited efficacy and undesirable side-effects. Patients with chronic cough describe sensory symptoms suggestive of upper airway and laryngeal neural

Chronic cough has been suggested to be due to three conditions, asthma, post nasal drip, and reflux disease. A different paradigm has evolved in which cough is viewed as the primary

We postulate that most patients with chronic cough have a single discrete clinical entity: Cough Hypersensitivity Syndrome. We constructed a questionnaire that elicits the major For many years patients with chronic cough have been investigated in an attempt to diagnose the cause of the cough. Here I suggest that the overwhelming majority of patients The symptoms of cough hypersensitivity may not distinguish between asthmatic cough and RCC. This suggests that chronic cough is the primary diagnosis in both

Cough reflex is a vital protective mechanism against aspiration, but when dysregulated, it can become hypersensitive. In fact, chronic cough is a significant medical Cough hypersensitivity syndrome A large proportion of patients who either do not have one of the common causes of chronic cough, or have had these causes addressed

診断がつかない慢性咳嗽の切り口 難治性の咳嗽を呈する患者について調べていた際に、咳過敏症候群：cough hypersensitivity syndrome（CHS）という概念を知りました。 Cough is an intrinsic protective reflex. However, chronic cough affects a considerable proportion of general population and has a major impact on quality of life. A recent paradigm shift to 大部分患者针对病因治疗后咳嗽均能得到有效缓解，但仍有一部分患者经过全面检查后仍未能明确病因，咳嗽敏感性增高是此类患者的重要临床与病理生理特征，临床上则用咳嗽高敏感综合征

Cough is an intrinsic protective reflex. However, chronic cough affects a considerable proportion of general population and has a major impact on quality of life. A Chronic some non cough is defined as a persistent cough, lasting beyond 8 weeks, poses a global health challenge, impacting a substantial portion of the world’s population. In the United

Cough reflex is a vital protective mechanism against aspiration, but when dysregulated, it can become hypersensitive. In fact, chronic cough is a sig-nificant medical

Cough hypersensitivity Over one in ten people in the UK will suffer from chronic cough and 20% of these cases will not respond to medical management1. Intervention from a Speech and Therapie nach RKI Abstract Chronic cough is a difficult to treat symptom of many respiratory and some non-respiratory diseases, indicating that varied pathologies can underpin the development of